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Future Perspective
Our observations may be crucial for the further development of both treatment and research strategy in gastric cancer. In this scenario, our data may help towards designing future clinical trials with the aim of investigating the outcome of different chemotherapy regimens in different patient groups prospectively stratified according to angiogenesis profile. Taxane-based and/or angiogenetic targeted-based therapeutic regimens may in fact represent interesting alternative options for patients deemed resistant to platinum-based combinations. Prospective trials will be essential for a full understanding and consequent clinical application of these treatment approaches.
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