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Are stem cells the therapy of the future for virtually all neurologic diseases from The answer is neither. Stem cells will likely be a powerful part of the therapeutic armamentarium of neurologists in years and decades to come. In some cases they will slow disease progression. In others, stem cells, combined with other therapies, may modestly increase function. And rarely, stem cells may markedly reduce disability or cure disease. Conversely, in some diseases stem cells are likely to never be effective, and the journey from animal model success to clinical therapy will be longer than many expect. This editorial will assess the likely future role of stem cells in combating neurologic diseases 5-10 years in the future. We will discuss the biological foundation and current applications of stem cells, focusing on two specific areas: endogenous neural stem cells and their capacity to repair injury, and myelinating precursors and their application to demyelinating disorders.
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